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A review of the first month of Wellcome Open Research by Michael Markie, Publisher, F1000, and Robert Kiley, Head of Digital Services, Wellcome. It’s been…

Professor Charles Bangham, Head of the Division of Infectious Diseases in the Faculty of Medicine at Imperial College London, recently published an article on the association of free serum haemoglobin with brain atrophy in secondary progressive multiple sclerosis on Wellcome Open Research. In this blog post he summarises the findings, what implications they have for the treatment of the disease and why he decided to publish the article on our platform.

María Rodríguez-López and Cristina Cotobal, Postdoctoral Fellows in Jürg Bähler’s lab at University College London recently published a very detailed Method Article on a new CRISPR/Cas9-based protocol and primer design tool. We asked them to explain what CRISPR/Cas9 is, what it can be used for and why they decided to publish their article on our platform.

‘Hepitopes’ is a new online resource, comprising a database of immune responses to Hepatitis B virus (HBV). We believe this will be an important resource for the HBV research community, with implications that range from characterising the basic science of virology and immunology, through to informing vaccine design and understanding clinical outcomes of infection. The database is designed as a live interactive resource that will evolve and develop over time, with improvements in the quality and content of the data, links to other tools and resources, and the potential to underpin scientific dialogue and new collaborations.

We spoke to Jim Smith (JS), head of the Developmental Biology Laboratory, and Tim Mohun (TM), head of the Heart Development Laboratory at the Francis Crick Institute about the research they published on Wellcome Open Research today, the benefits of the platform and why they think other Wellcome grantees should follow their lead.

At Wellcome, we are committed to improving health for everyone by helping great ideas to thrive. Our researchers are central to this. The accessibility of the work that they do greatly affects the impact that it can have on improving health. Wellcome Open Research is our latest action to support the publication of the research we fund in a way that we think increases its potential impact.